When moody teenager Quinn moves to a sleepy town, she makes new friends and crosses paths with the local mascot: a sinister, ever-grinning clown called Frendo.
About to embark on a world tour, global pop sensation Skye Riley (played by Naomi Scott) begins experiencing increasingly terrifying and inexplicable events.
After pre-teen Isaac loses his father in a car accident, the newly orphaned boy and his responsibility-fearing stepmother Laura live an isolated life in the countryside until Isaac's father returns in grotesquely unimaginable ways.
This grotesque body horror satire follows washed-out actress Elisabeth Sparkle (Demi Moore) grappling with aging and dwindling popularity, so she starts consuming a black-market drug simply known as the "substance."